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Cancer survivors at greater risk of subsequent primary cancers

Survivors of adult-onset cancers run a greater risk of developing and dying from subsequent primary cancers (SPCs) than the general population. The retrospective cohort study, reported in JAMA (December 22), found cancers…

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Highlights of 2020 San Antonio Breast Cancer Symposium

In 2020, the San Antonio Breast Cancer Symposium (SABCS) co-organised in association with the American Association for Cancer Research (AACR) celebrated its 43rd year as the world’s premier annual breast oncology meeting.…

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Immunotherapy cardiotoxicity higher than previously estimated

Cancer patients receiving immunotherapy drugs have a much higher incidence of cardiac events than previous estimates from pharmacovigilance data, reports a nationwide Danish registry. The study, published in the European Heart Journal,…

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NHS England’s pilot of cancer screening blood test raises questions

The UK National Health Service (NHS) announced on the 27 November that it would be piloting an early detection multi-cancer blood test next year.  This represents an important advance because “every year,…

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Building back cancer services after Covid-19: European Cancer Organisation plan

The European Cancer Organisation has proposed seven urgent recommendations to ‘build back cancer services better’ after the ongoing challenges resulting from the Covid-19 pandemic. ‘The Impact of COVID-19 on Cancer in Europe’,…

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Prolonged ADT use in prostate cancer increases CV mortality: A need for cardiovascular protection

Prolonged androgen deprivation therapy (ADT) exposure was found to be associated with reduced cardiorespiratory fitness (CRF) and increased cardiovascular (CV) mortality. The study, published in JACC: CardioOncology, emphasizes the need to consider…

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Serious patient-reported outcomes data gap in immunotherapy trials revealed

A review of trials of immunotherapy agents revealed a ‘considerable gap’ in the use of patient reported outcomes (PROs), reports a recent study. The data analysis study found PROs were included in…

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Machine learning mortality predictions boost end-of-life conversations

A study of the use of machine learning to predict the risk of dying within six months, combined with behavioural nudges, led to increased serious illness conversations between oncologists and cancer patients.…

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Two studies provide ‘building blocks’ for future advances in pancreatic cancer

Two recently published studies have provided insights into new ways of tackling pancreatic ductal adenocarcinomas (PDACs), a cancer where survival outcomes have made little progress in the past few decades. Approximately 95%…

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Roundtable ‘grasps nettle’ on European cancer inequalities

Improving treatment of older patients and closing the East−West divide were the focus of a Community 365 Roundtable on Inequalities organised by the European Cancer Organisation on the 14th October. This event was the first of a series of Community 365 roundtable meetings. Community 365 is an European Cancer Organisation initiative that brings together charity, […]