chemotherapy

Articles

Strategies Needed to Prioritise Screening in Survivors of Childhood Cancer

Survivors of childhood cancer experience accelerated onset of ageing-related diseases, regardless of prior radiation exposure. The simulation modelling study, published in JAMA Oncology, online March 20, found that chronic health conditions developed…

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Breast cancer treatments may accelerate ageing

Breast cancer treatments activate genes associated with biological ageing. The study, published in the Journal of the National Cancer Institute, 8 October, suggests that chemotherapy, radiation, and surgery all lead to statistically…

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Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy

Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science…

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Older adults with advanced cancers may do better on modified regimens

Lowering the dose and adjusting the schedule may help older adults with advanced cancer better tolerate chemotherapy. The cohort study, published in JAMA Network Open, February 15, found older patients with advanced…

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Quality care, free of charge, and closer to home: expanding access to cancer services in India

Rahul Jain and his mother Shashi were in Pune – 1,000 km from their home in Ashoknagar, in the neighbouring state of Madhya Pradesh – when they were told there was no…

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Chemobrain: it’s real, it’s troublesome and it deserves more attention

Fiona Henderson was part way through her psychology degree when she received her breast cancer diagnosis. Right after treatments finished, she returned to her studies – initially without a problem. “Three or…

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Study suggests prehabilitation should become standard of care in oesophageal cancer

Enrolling oesophageal cancer patients in prehabilitation exercise programmes can boost tumour regression during chemotherapy. The small study, published in British Journal of Sports Medicine (online 1 February, 2022), demonstrated improved pathological, radiological and…

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Drugs shortages: ‘We parents of children with cancer are too exhausted to protest’

When it all started, Ioana Oprea did not have a spare moment to come to terms with what had happened ‒ to truly take in the fact that her son Teodor had…

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Immunotherapy plus chemo: benefits in lung cancer neoadjuvant treatment

Adding a check point inhibitor to chemotherapy as neoadjuvant treatment for resectable non-small cell lung cancer (NSCLC) produced significant improvements of pathological complete response (pCR) in comparison to chemotherapy alone. The CheckMate-816…

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Right drug, wrong patient: here’s how we improve our targeting

When it comes to precision and personalised medicine (PPM), clinical practice in oncology takes pride in developing and administering treatments that selectively target components of tumour cells. But, PPM is a model that also takes into account the inherent variability of patients’ genetic, environmental and lifestyle factors, to identify which treatments would be most effective […]