mutational signatures

Articles

Meet the Man Decoding the Origins of Cancer

Many people diagnosed with cancer often wonder what “caused” their disease and whether they could have done anything to prevent it. Typically, the risk of developing cancer is determined by a combination…

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CancerWorld #109 (November 2025)

Where leadership, legacy, and discovery meet the future of care Every issue of CancerWorld tells a story about connection, between science and humanity, between personal courage and collective change. The November edition…

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100,000 Genomes Project pinpoints new cancer genetic culprits

DNA analysis of thousands of tumours in the 100,000 Genomes project has uncovered a ‘treasure trove’ of 58 new mutational signatures causing cancer. The study, published in Science, 21 April, showed that…