There have been great strides in our understanding of cancer genomics - the mutational events that lead to high cancer risks and those that drive progression in cancer patients. Using vast databases…
Every year, around 2.3 million people across the globe are diagnosed with breast cancer. For lack of access to the right diagnostic test, many of them are being treated with chemotherapy that…
RAS oncogenes and their proteins have central roles in almost all cancers, including leukaemias, multiple myelomas, skin cancers and many solid tumours, making the RAS protein family an ideal cancer target. But…
CRISPR is a revolutionary gene-editing tool that allows scientists to cut DNA with extraordinary precision and make changes to the genome. The technology was a gift to cancer researchers, whose efforts to…
Precision medicine is transforming the way we treat cancer. Oncology is evolving from treating purely on the basis of a broad indication to a tailored approach that is based on a tumour’s…
Developments in molecular diagnostics are allowing us to capture an extraordinarily detailed picture of the genomic and other molecular changes that characterise a given tumour specimen. But making best use of the…
Precision cancer medicine aims to improve diagnosis and treatment at the molecular level. Although genomics has influenced what precision medicine encompasses today, research is at a turning point. There is currently a…
The nature of the doctor–patient relationship has gone through various phases in history, based on the changing role of the physician in the community, as well as progress in medicine and increased…
“Something that hit me pretty early during my residency as an oncologist was that sex in most cases is a clear-cut binary, pretty obvious biological variable affecting attitudes as well as tolerance…
Current access to high quality oncology biomarker testing across Europe is inconsistent and contributes to health inequalities. To address barriers to biomarker testing, the ‘Unlocking the potential of precision medicine in Europe’…
