repurposing

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Study opens way for using antifibrotic drugs to prevent metastasis

Adding a drug currently used against idiopathic pulmonary fibrosis to chemotherapy in the neoadjuvant setting increased event-free survival in patients with early HER2-negative breast cancer. The study, published in Clinical Cancer Research,…

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Can a novel anti-diabetic, anti-obesity ‘wonder drug’ be repurposed for cancer?

Throughout human history, the search for a universal cure has captivated the minds of philosophers, healers and scientists across time and cultures. In Greek mythology, the goddess Panacea was believed to possess…

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Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy

Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science…

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Could covid-19 boost interest in drug repurposing in oncology?

Could the frantic search for drugs to treat patients severely affected by the covid-19 virus be a shot in the arm for new cancer treatments? There have been many headlines about repurposed agents, such as the highly debated antimalarial drug hydroxychloroquine or tocilizumab, an anti-rheumatic drug targeting Il-6. Along with many others, the research to […]

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Non-cancer drugs repurposing, a new trick to win the onco-challenge?

Originally developed and approved for use in diabetes, inflammation and other non-oncological diseases (even osteoarthritis in dogs), many drugs could have a pivotal role in treating cancer. And they could be more abundant than expected, according to a paper recently published in Nature Cancer. “Anticancer uses of non-oncology drugs have occasionally been found, but such […]