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Aspirin prevents colorectal cancer best in those with least healthy lifestyles

Regular aspirin may help lower risk of colorectal cancer most effectively in people who have greater lifestyle-related risk factors for the disease. The study, published in JAMA Oncology on 1 August, found…

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Endometriosis: impact on ovarian cancer varies by subtype

Women with endometriosis have a fourfold higher risk of any type of ovarian cancer and those with severe endometriosis a 10 fold higher risk compared to women who do not have the…

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Disadvantaged neighbourhoods may contribute to racial disparities in risk of aggressive prostate cancer

Men with prostate cancer living in disadvantaged neighbourhoods show significantly higher activity of stress-related genes than those living in other neighbourhoods. The observational study, published in JAMA Network Open, 12 July, found…

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Exercise boosts anti-tumour immune cells in people with breast cancer

Just 30 minutes of exercise increases the proportion of tumour-killing immune cells in the blood of people with breast cancer. The Finnish study, published in Frontiers in Immunology, 24 June, found that…

Articles

Treatment-free remission: How today’s CML patients can aspire to a drug-free life

Around the start of the millennium, the therapeutic landscape for chronic myeloid leukaemia (CML), a rare type of blood cancer affecting the bone marrow and white blood cells, was transformed by the…

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Liver biopsies can predict when and where pancreatic cancer will metastasise and may guide treatment of early-stage disease

Liver biopsies undertaken at the time of surgery for pancreatic cancer can be used to identify cellular and molecular markers that predict whether early pancreatic cancer will later metastasise to the liver.…

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Common blood pressure drug could be used in AML to cut cardiotoxicity and improve response to chemotherapy

Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science…

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Neoadjuvant immunotherapy delivers unprecedented pathological response in mismatch repair deficient non-metastatic colon cancers

In patients with non-metastatic colon cancer who have mismatch repair deficient tumours, a short course of neoadjuvant immunotherapy (one cycle ipilimumab and two cycles nivolumab) was highly effective. The NICHE-2 trial, published…

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Generation X will experience higher rates of cancer than earlier generations

At age 60 members of Generation X, defined as people born between 1965 and 1980, are projected to have higher rates of cancer than Baby Boomers, born between 1946 and 1964. The…

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Tailoring palliative care visits to patients’ needs saves resources without harm

Stepped palliative care, with visits occurring only at key points in the patient’s cancer journey, resulted in fewer palliative care visits than conventional early palliative care. The study, presented at the American…