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Rise in initiation of immunotherapy at the end of life

Immunotherapy is increasingly being initiated in the month prior to death in patients with stage IV non-small-cell lung cancer, melanoma, and renal cell carcinoma. The US study, published in JAMA Oncology, online…

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Flaxseed could provide protection against breast cancer

Components of flaxseed may help to prevent the development of breast cancer. The mouse study, published in Microbiology Spectrum, 7 December 2023, uncovers a novel link between flaxseed consumption in the diet,…

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Inequalities in cancer mortality highlight need to adapt approaches to local conditions

The risk of dying from cancer is highest for men and women living in areas with greater poverty. A study into small-area variations in cancer mortality statistics between different English health districts,…

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Exercise boosts quality of life in metastatic breast cancer

People with metastatic breast cancer taking part in a nine-month structured exercise programme report less fatigue and improved quality of life in comparison to controls. The study, abstract GS02-10, presented at the…

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A European roadmap to improve men’s cancer outcomes

Ensuring gender-neutral HPV vaccination, more flexible GP access hours, and national cancer plans tackling gender specific needs are among the policies that have been identified to improve male cancer outcomes. The roadmap…

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Regular mammography offers best insurance against dying from breast cancer

Women who regularly attend breast screening mammography have a reduced risk of breast cancer mortality. The Swedish study, Abstract R1-SSBR10, presented at the annual meeting of the Radiological Society of North America…

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Potential new target to prevent pancreatic cancer from spreading to liver

A mechanism that facilitates pancreatic cancer cells spreading to the liver has been elucidated. The study, published in Cell Reports, 2 November, identifies a ‘therapeutic vulnerability’ where the protein Netrin-1, which is…

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Study indicates people with type 2 diabetes need increased colorectal cancer screening

People with type 2 diabetes have a 47% increased risk of developing colorectal cancer (CRC) in comparison to people without diabetes. The cohort study, published in Jama Network Open, 15 November, suggests…

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Induction chemotherapy delivers first survival benefit in locally advanced cervical cancer for two decades

A short course of induction chemotherapy prior to chemoradiation improved survival in locally advanced cervical cancer. The study, presented in a Presidential Symposium at the ESMO 2023 Congress, abstract LBA8, found that…

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Ultra-sensitive immunoassay detects key protein produced by cancer cells

A blood test detecting a key protein produced by cancer cells is showing promise as an early indicator of cancer. The study, published in Cancer Discovery, September 12, suggests that the ultra-sensitive…