News

Gut microbiome offers new avenue for detecting colorectal cancer

Significant variations in the gut microbiome can be identified between people who develop pre-cancerous colonic lesions and those who do not. The Dutch study, abstract OP118, presented at United European Gastroenterology (UEG)…

News

Machine learning improves accuracy of survival prediction

An artificial intelligence prototype has been developed to estimate the survival of newly diagnosed cancer patients with breast, thyroid, and pancreatic cancers. The study, abstract 4160, presented at the American College of…

News

Walkable neighbourhoods lower risk of obesity related cancers

Women living in US neighbourhoods with higher levels of ‘walkability’ have lower risks of obesity related cancers, including postmenopausal breast, endometrial, ovarian, and multiple myeloma. The prospective study, published in Environmental Health…

News

Dichloroacetate shows promise in treating cancer-related fatigue

Dichloroacetate, a drug targeting the metabolism, helped alleviate cancer related fatigue in mouse models of melanoma and colon cancer, reports a study published in the American Journal of Physiology Endocrinology and Metabolism, 2…

News

Combination immunotherapy with novel immune-oncology agents benefit NSCLC patients in presurgical setting

Patients with resectable non-small-cell lung cancer show improved major pathological response rates with combination immune oncology agents versus single-agent immunotherapy. The NeoCOAST trial, published in Cancer Discovery, 14 September, demonstrated that combining…

News

Trial defines breast cancer population who can omit sentinel node biopsy

Breast cancer patients with no axillary lymph node involvement apparent on ultrasound scans, and with tumours less than 2cm, had similar outcomes regardless of whether they underwent sentinel lymph node biopsy or…

News

Statin use lowers risk of colorectal cancer in inflammatory bowel disease

Statin use was associated with a lower risk of colorectal cancer, colorectal cancer related mortality, and all-cause mortality in a patient population with inflammatory bowel disease. The Swedish study, published online in…

News

New drug breaks through fibrotic tissue in pancreatic cancer

A drug targeting scar-like ‘fibrotic’ tissue within tumours shows promise for treating pancreatic ductal adenocarcinoma (PDAC). In the study, reported online in Nature Cancer, 28 August, Australian investigators showed in mouse and…

News

Anti-oestrogen provides novel strategy to boost checkpoint inhibitors

Adding anti-oestrogen therapy improves response to combined chemotherapy and immune checkpoint inhibition in tumours that do not express oestrogen receptors. The Japanese study, published in British Journal of Cancer, provides a new…

News

Anticancer benefits from Mediterranean ‘lifestyle’ can be transferred to non-Mediterranean population

High adherence to a ‘Mediterranean lifestyle’ is associated with lower cancer mortality in a dose-responsive manner. The study, published in Mayo Clinic Proceedings (16 August), showed that UK adults who are the…